Understanding Vaping: Can It Cause Sickness? Teen who was put on life support for vaping says 'I didn't think of myself as a smoker' ABC News Vape explosion leaves Bakersfield teen with amputated fingers and burns, family speaks out Sometimes when people vape for the first time they can feel quite unwell and, in some cases, they can actually be sick. This is due to the nicotine they're ingesting and is Does Vaping Make You Tired? Either Nicotine or Cannabis Vaping FAQs: Why do I feel sick after Vaping?